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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
24.55
Human Site:
S1365
Identified Species:
45
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
S1365
L
M
L
E
P
Y
G
S
Q
R
D
I
A
Y
V
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S1379
L
M
L
E
P
Y
G
S
Q
R
D
I
A
Y
V
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
S1365
L
M
L
E
P
Y
G
S
Q
R
D
I
A
Y
V
Dog
Lupus familis
XP_537704
2182
240593
S1373
L
M
L
E
P
Y
G
S
Q
R
D
I
A
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
S1364
L
M
L
E
P
Y
G
S
Q
R
D
I
A
Y
V
Rat
Rattus norvegicus
NP_001100505
2040
223488
D1259
G
A
R
S
F
F
R
D
L
T
A
I
Y
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
Y1362
E
R
L
M
L
E
P
Y
G
S
Q
R
D
I
A
Chicken
Gallus gallus
XP_415884
2225
244861
S1416
L
M
L
E
P
Y
G
S
Q
R
D
V
A
Y
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
P1309
S
P
E
P
L
P
I
P
T
L
L
V
G
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
K1807
L
Q
N
A
F
H
C
K
S
R
G
G
S
G
S
Honey Bee
Apis mellifera
XP_393643
1982
216109
Y1201
I
P
A
L
V
V
G
Y
D
R
D
W
L
S
L
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
Q1866
A
G
L
G
P
V
D
Q
P
K
D
V
M
Y
I
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
D346
L
M
I
G
H
D
K
D
W
L
S
S
S
P
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
6.6
93.3
N.A.
6.6
N.A.
13.3
20
26.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
6.6
100
N.A.
13.3
N.A.
26.6
33.3
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
0
0
0
0
0
8
0
47
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
16
8
0
62
0
8
0
0
% D
% Glu:
8
0
8
47
0
8
0
0
0
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
16
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
8
0
16
0
0
54
0
8
0
8
8
8
8
0
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
8
0
0
0
0
47
0
8
8
% I
% Lys:
0
0
0
0
0
0
8
8
0
8
0
0
0
0
0
% K
% Leu:
62
0
62
8
16
0
0
0
8
16
8
0
8
0
8
% L
% Met:
0
54
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
8
54
8
8
8
8
0
0
0
0
8
0
% P
% Gln:
0
8
0
0
0
0
0
8
47
0
8
0
0
0
0
% Q
% Arg:
0
8
8
0
0
0
8
0
0
62
0
8
0
0
0
% R
% Ser:
8
0
0
8
0
0
0
47
8
8
8
8
16
8
16
% S
% Thr:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% T
% Val:
0
0
0
0
8
16
0
0
0
0
0
24
0
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
47
0
16
0
0
0
0
8
62
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _